Molecular weight (DA)
17kD
Immunogen
The antiserum was produced against synthesized peptide derived from human JTB. AA range:10-59
Specificity
JTB Polyclonal Antibody detects endogenous levels of JTB protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the JTB family.,tissue specificity:Expressed in all normal human tissues studied but overexpressed in most of their malignant counterparts.,
Function
similarity:Belongs to the JTB family.,tissue specificity:Expressed in all normal human tissues studied but overexpressed in most of their malignant counterparts.,
Other name
JTB; HSPC222; Protein JTB; Jumping translocation breakpoint protein; Prostate androgen-regulated protein; PAR protein
Human protein sequence Database
O76095
Mouse protein sequence database
O88824
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein . Mitochondrion . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
Tissue expression
Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.
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