Molecular weight (DA)
98kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PTGFRN. AA range:601-650
Specificity
CD315 Polyclonal Antibody detects endogenous levels of CD315 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.,sequence caution:Translated as Gln.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151.,
Function
function:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.,sequence caution:Translated as Gln.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151.,
Protein name
Prostaglandin F2 receptor negative regulator
Other name
PTGFRN; CD9P1; EWIF; FPRP; KIAA1436; Prostaglandin F2 receptor negative regulator; CD9 partner 1; CD9P-1; Glu-Trp-Ile EWI motif-containing protein F; EWI-F; Prostaglandin F2-alpha receptor regulatory protein; Prostaglandin F2-alpha receptor-associated protein; CD315
Human protein sequence Database
Q9P2B2
Mouse protein sequence database
Q9WV91
Rat protein sequence database
Q62786
Cellular localization
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein .
Tissue expression
Brain,Embryo,Epithelium,Heart,Liver,PCR rescued clones,
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