Molecular weight (DA)
65kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ADCK4. AA range:31-80
Specificity
ADCK4 Polyclonal Antibody detects endogenous levels of ADCK4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein with two copies of a domain found in protein kinases. The encoded protein has a complete protein kinase catalytic domain, and a truncated domain that contains only the active and binding sites of the protein kinase domain, however, it is not known whether the protein has any kinase activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Function
function:The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).,similarity:Belongs to the protein kinase superfamily. ADCK protein kinase family.,similarity:Contains 1 protein kinase domain.,
Protein name
Uncharacterized aarF domain-containing protein kinase 4
Other name
ADCK4; Uncharacterized aarF domain-containing protein kinase 4
Human protein sequence Database
Q96D53
Mouse protein sequence database
Q566J8
Rat protein sequence database
Q6AY19
Cellular localization
Mitochondrion membrane ; Single-pass membrane protein . Cytoplasm, cytosol . Cell membrane .
Tissue expression
Widely expressed, including renal podocytes.
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