Molecular weight (DA)
45kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PHKG1. AA range:241-290
Specificity
PHKG1 Polyclonal Antibody detects endogenous levels of PHKG1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],
Function
catalytic activity:2 ATP + phosphorylase b = 2 ADP + phosphorylase a.,domain:The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.,function:Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin.,
Protein name
Phosphorylase b kinase gamma catalytic chain skeletal muscle isoform
Other name
PHKG1; PHKG; Phosphorylase b kinase gamma catalytic chain; skeletal muscle isoform; Phosphorylase kinase subunit gamma-1
Fields
>>Calcium signaling pathway;>>Insulin signaling pathway;>>Glucagon signaling pathway
Human protein sequence Database
Q16816
Mouse protein sequence database
P07934
Rat protein sequence database
Cellular localization
cytosol,phosphorylase kinase complex,
Tissue expression
PCR rescued clones,Salivary gland,Skeletal muscle,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车