Molecular weight (DA)
17kD
Immunogen
Synthesized peptide derived from human Cleaved-Ephrin-A4 (S170)
Specificity
This antibody detects endogenous levels of Human,Mouse Cleaved-Ephrin-A4 (S170, protein was cleaved amino acid sequence between 170-171 )
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
function:May play a role in the interaction between activated B lymphocytes and dendritic cells in tonsils.,similarity:Belongs to the ephrin family.,tissue specificity:Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines.,
Function
cell-cell signaling,
Gene Name
EFNA4 EPLG4 LERK4
Protein name
Cleaved-Ephrin-A4 (S170)
Other name
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4;LERK-4)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>PI3K-Akt signaling pathway;>>Axon guidance;>>MicroRNAs in cancer
Human protein sequence Database
P52798
Mouse protein sequence database
O08542
Rat protein sequence database
Cellular localization
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 2]: Secreted .
Tissue expression
Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines.