Immunogen
The antiserum was produced against synthesized peptide derived from human GDF-8. AA range:38-87
Specificity
GDF-8 Polyclonal Antibody detects endogenous levels of GDF-8 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],
Function
function:Acts specifically as a negative regulator of skeletal muscle growth.,online information:Myostatin entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity.,
Protein name
Growth/differentiation factor 8
Other name
MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin
Fields
>>Cytokine-cytokine receptor interaction
Human protein sequence Database
O14793
Mouse protein sequence database
O08689
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Colon,Muscle,Pericardium,Skeletal muscle,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车