Molecular weight (DA)
36kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Annexin III. AA range:15-64
Specificity
Annexin III Polyclonal Antibody detects endogenous levels of Annexin III protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008],
Function
domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,
Other name
ANXA3; ANX3; Annexin A3; 35-alpha calcimedin; Annexin III; Annexin-3; Inositol 1; 2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III; PAP-III
Human protein sequence Database
P12429
Mouse protein sequence database
O35639
Rat protein sequence database
Cellular localization
cytoplasm,plasma membrane,membrane,axon,dendrite,phagocytic vesicle membrane,specific granule,neuronal cell body,extracellular exosome,
Tissue expression
Aorta endothelial cell,Cervix,Colon carcinoma,Platelet,
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