Molecular weight (DA)
22kD
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IFNA1/13. AA range:140-189
Specificity
IFN-α1 Polyclonal Antibody detects endogenous levels of IFN-α1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],
Function
function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family.,
Protein name
Interferon alpha-1/13
Other name
IFNA1; IFNA13; Interferon alpha-1/13; IFN-alpha-1/13; Interferon alpha-D; LeIF D
Fields
>>Cytokine-cytokine receptor interaction;>>PI3K-Akt signaling pathway;>>Necroptosis;>>Toll-like receptor signaling pathway;>>NOD-like receptor signaling pathway;>>RIG-I-like receptor signaling pathway;>>Cytosolic DNA-sensing pathway;>>JAK-STAT signaling pathway;>>Natural killer cell mediated cytotoxicity;>>Alcoholic liver disease;>>Tuberculosis;>>Hepatitis C;>>Hepatitis B;>>Measles;>>Human cytomegalovirus infection;>>Influenza A;>>Human papillomavirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Herpes simplex virus 1 infection;>>Epstein-Barr virus infection;>>Human immunodeficiency virus 1 infection;>>Coronavirus disease - COVID-19;>>Pathways in cancer;>>Autoimmune thyroid disease;>>Lipid and atherosclerosis
Human protein sequence Database
P01562
Mouse protein sequence database
P01572
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Cerebellum,Leukocyte,
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