Molecular weight (DA)
28kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB7L1. AA range:115-164
Specificity
Rab 7L1 Polyclonal Antibody detects endogenous levels of Rab 7L1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
Function
similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
Protein name
Ras-related protein Rab-7L1
Other name
RAB7L1; Ras-related protein Rab-7L1; Rab-7-like protein 1
Human protein sequence Database
O14966
Mouse protein sequence database
Q91YQ1
Rat protein sequence database
Q63481
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus . Golgi apparatus, trans-Golgi network . Vacuole . Cytoplasm, cytoskeleton . Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (PubMed:29212815). Colocalizes with GM130 at the Golgi apparatus (PubMed:22042847). Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus (PubMed:22042847). Colocalizes with TGN46 at the trans-Golgi network (TGN) (PubMed:24788816). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery (PubMed:22042847). .
Tissue expression
Ubiquitous.
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