Molecular weight (DA)
34kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AQP12. AA range:231-280
Specificity
AQP12 Polyclonal Antibody detects endogenous levels of AQP12 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.,tissue specificity:Restricted to the pancreas.,
Function
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.,tissue specificity:Restricted to the pancreas.,
Protein name
Aquaporin-12A/B
Other name
AQP12A; AQP12; AQPX2; Aquaporin-12A; AQP-12; AQP12B; Aquaporin-12B; AQP-12B
Human gene ID
375318/653437
Human protein sequence Database
Q8IXF9/A6NM10
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Restricted to the pancreas.
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