Molecular weight (DA)
48kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CADM4. AA range:339-388
Specificity
IGSF4C Polyclonal Antibody detects endogenous levels of IGSF4C protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.,PTM:N-glycosylated.,similarity:Belongs to the nectin family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Monomer and homodimer.,tissue specificity:Expressed in brain, prostate, brain, kidney and some other organs.,
Function
function:Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.,PTM:N-glycosylated.,similarity:Belongs to the nectin family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Monomer and homodimer.,tissue specificity:Expressed in brain, prostate, brain, kidney and some other organs.,
Protein name
Cell adhesion molecule 4
Other name
CADM4; IGSF4C; NECL4; TSLL2; Cell adhesion molecule 4; Immunoglobulin superfamily member 4C; IgSF4C; Nectin-like protein 4; NECL-4; TSLC1-like protein 2
Human protein sequence Database
Q8NFZ8
Mouse protein sequence database
Q8R464
Rat protein sequence database
Q1WIM1
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Expressed in brain, prostate, brain, kidney and some other organs.
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