Molecular weight (DA)
42kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NT. AA range:235-284
Specificity
Neurotrimin Polyclonal Antibody detects endogenous levels of Neurotrimin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009],
Function
function:Neural cell adhesion molecule.,similarity:Belongs to the immunoglobulin superfamily. IgLON family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
Other name
NTM; IGLON2; NT; Neurotrimin; hNT; IgLON family member 2
Human protein sequence Database
Q9P121
Mouse protein sequence database
Q99PJ0
Rat protein sequence database
Cellular localization
Cell membrane; Lipid-anchor, GPI-anchor.
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