Molecular weight (DA)
81kD
Immunogen
Synthesized peptide derived from human P3H1
Specificity
This antibody detects endogenous levels of P3H1 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, and 0.1909% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
Gene Name
LEPRE1 GROS1 P3H1 PSEC0109
Protein name
Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1)
Human protein sequence Database
Q32P28
Mouse protein sequence database
Q3V1T4
Rat protein sequence database
Q9R1J8
Cellular localization
[Isoform 1]: Endoplasmic reticulum.; Secreted, extracellular space, extracellular matrix . Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG).
Storage
‘-15°C to -25°C/1 year(Do not lower than -25°C)
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