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MYLK Rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-17743

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Molecular Weight Calculated MW: 211 kDa; Observed MW: 130-140 kDa
Immunogen
A synthesized peptide derived from human Myosin light chain kinase
Specificity
Source
Formulation
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Purification process (Immunogen)
Concentration
Background
Regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological and asthmatic airway resistance.
Function
Gene Name
MYLK
Protein name
Abbreviation
Other name
KMLS; KRP; MLCK; MYLK; myosin light chain kinase; smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin
Fields
Human gene ID
SwissProt ID Q15746
Human protein sequence Database
Gene ID 4638
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Tissue expression
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Experimental scheme>

Procedure

Citation>

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MYLK Rabbit pAb

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