Molecular weight (DA)
Molecular Weight
Calculated MW: 78 kDa; Observed MW: 78 kDa
Immunogen
A synthetic peptide of human Apg7
Dilution rate
WB: 1/500-1/1000
Purification process (Immunogen)
Background
The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
Other name
hAGP7; Ubiquitin-activating enzyme E1-like protein; APG7L
Human gene ID
SwissProt ID
O95352
Human protein sequence Database
Gene ID
10533
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.