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Phospho-Chk2 (Thr68) Rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-17867

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Molecular Weight Calculated MW: 61 kDa; Observed MW: 61 kDa
Immunogen
The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68.
Specificity
Source
Formulation
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Purification process (Immunogen)
Concentration
Background
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Function
Gene Name
CHEK2
Protein name
Abbreviation
Other name
CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
Fields
Human gene ID
SwissProt ID O96017
Human protein sequence Database
Gene ID 11200
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Tissue expression
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Experimental scheme>

Procedure

Citation>

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Phospho-Chk2 (Thr68) Rabbit pAb

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