Molecular weight (DA)
23kD
Immunogen
Synthesized peptide derived from human FNDC5
Specificity
This antibody detects endogenous levels of FNDC5 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
[Irisin]: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
Protein name
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
Human protein sequence Database
Q8NAU1
Mouse protein sequence database
Q8K4Z2
Rat protein sequence database
Q8K3V5
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Peroxisome membrane ; Single-pass type I membrane protein . Imported in peroxisomes through the PEX5 receptor pathway. .; [Irisin]: Secreted. Detected in the blood of individuals subjected to endurance exercise. .
Tissue expression
Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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