Molecular weight (DA)
57kD
Immunogen
Synthesized peptide derived from human ARFGAP2
Specificity
This antibody detects endogenous levels of ARFGAP2 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Gene Name
ARFGAP2 ZNF289 Nbla10535
Protein name
ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289)
Human protein sequence Database
Q8N6H7
Mouse protein sequence database
Q99K28
Rat protein sequence database
Q3MID3
Cellular localization
Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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