Molecular weight (DA)
140kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SFRS15. AA range:601-650
Specificity
SFRS15 Polyclonal Antibody detects endogenous levels of SFRS15 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene likely encodes a member of the arginine/serine-rich splicing factor family. A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
Function
function:May act to physically and functionally link transcription and pre-mRNA processing.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 CID domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with the repetitive C-terminal domain (CTD) of RNA polymerase II.,
Protein name
Splicing factor arginine/serine-rich 15
Other name
SCAF4; KIAA1172; SFRS15; Splicing factor; arginine/serine-rich 15; CTD-binding SR-like protein RA4; SR-related and CTD-associated factor 4
Human protein sequence Database
O95104
Mouse protein sequence database
Rat protein sequence database
Q63627
Cellular localization
Nucleus .
Tissue expression
Brain,Epithelium,Melanoma,Pancreas,Testis,Uterus,
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