Molecular weight (DA)
147kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1030-1110
Specificity
MYO3B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Probable actin-based motor with a protein kinase activity.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 IQ domains.,similarity:In the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.,tissue specificity:Expressed in retina, kidney and testis.,
Protein name
Myosin-IIIb (EC 2.7.11.1)
Human protein sequence Database
Q8WXR4
Mouse protein sequence database
Q1EG27
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton. Cell projection, stereocilium .
Tissue expression
Expressed in retina, kidney and testis.
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