Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human SYTL1 AA range: 333-383
Specificity
This antibody detects endogenous levels of SYTL1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.101% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May act as Rab effector protein and play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-triphosphate.,similarity:Contains 1 C2 domain.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains.,subcellular location:Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.,subunit:Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus (By similarity). Binds NCF2.,tissue specificity:Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea.,
Gene Name
SYTL1 SLP1 SB146
Other name
Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1)
Human protein sequence Database
Q8IYJ3
Mouse protein sequence database
Q99N80
Rat protein sequence database
Cellular localization
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.
Tissue expression
Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).
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