Molecular weight (DA)
105kD
Immunogen
Synthesized peptide derived from human ZN268 AA range: 201-251
Specificity
This antibody detects endogenous levels of ZN268 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.196% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
developmental stage:Highly expressed in 3- to 5-week-old embryos.,function:May be involved in transcriptional regulation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 24 C2H2-type zinc fingers.,
Other name
Zinc finger protein 268 (Zinc finger protein HZF3)
Fields
>>Herpes simplex virus 1 infection
Human protein sequence Database
Q14587
Mouse protein sequence database
Rat protein sequence database
Cellular localization
[Isoform 1]: Nucleus .; [Isoform 2]: Nucleus . Cytoplasm .
Tissue expression
Overexpressed in ovarian cancer tissues compared to normal ovarian tissues. Isoform 1 and isoform 2 are expressed in squamous epithelium tissues. Isoform 2 is overexpressed in squamous cervical cancer (at protein level). Expressed in blood cells. Isoform 1 is expressed in pancreas, lung, skeletal muscle, heart, placenta, liver, kidney and brain. Isoform 2 expressed in chronic lymphocytic leukemia (CLL) and several tumor cell lines. Isoform 3 is expressed in several tumor cells. Isoform 5 is expressed in fetal liver and several tumor cells. Isoform 6 is weakly expressed in brain, lung amd small intestin and in several tumor cells. Isoform 7 is expressed in fetal liver and several tumor cells.
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