Immunogen
Synthesized peptide derived from human RBBP9 AA range: 108-158
Specificity
This antibody detects endogenous levels of RBBP9 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008],
Function
function:May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.,similarity:Belongs to the RBBP9 family.,tissue specificity:Widely expressed. Expressed at higher levels in tumor tissues than in normal tissues.,
Gene Name
RBBP9 BOG RBBP10
Human protein sequence Database
O75884
Mouse protein sequence database
O88851
Rat protein sequence database
O88350
Cellular localization
nucleus,nucleolus,cytoplasm,extracellular exosome,
Tissue expression
Expressed at higher levels in tumor tissues such as carcinoma.
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