Immunogen
Synthesized peptide derived from human FUCO2 AA range: 409-459
Specificity
This antibody detects endogenous levels of FUCO2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. [provided by RefSeq, Aug 2010],
Function
catalytic activity:An alpha-L-fucoside + H(2)O = L-fucose + an alcohol.,function:Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.,similarity:Belongs to the glycosyl hydrolase 29 family.,subunit:Homotetramer.,
Gene Name
FUCA2 PSEC0151 UNQ227/PRO260
Fields
>>Other glycan degradation;>>Lysosome
Human protein sequence Database
Q9BTY2
Mouse protein sequence database
Q99KR8
Rat protein sequence database
Q6AYS4
Cellular localization
Secreted .
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