Immunogen
Synthesized peptide derived from human WDR33 AA range: 319-369
Specificity
This antibody detects endogenous levels of WDR33 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 collagen-like domain.,similarity:Contains 7 WD repeats.,tissue specificity:Most highly expressed in testis.,
Fields
>>mRNA surveillance pathway
Human protein sequence Database
Q9C0J8
Mouse protein sequence database
Q8K4P0
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Most highly expressed in testis.
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