Immunogen
Synthesized peptide derived from human STP1 AA range: 4-54
Specificity
This antibody detects endogenous levels of STP1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1：50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008],
Function
function:In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.,similarity:Belongs to the nuclear transition protein 1 family.,tissue specificity:Testis.,
Human protein sequence Database
P09430
Mouse protein sequence database
P10856
Rat protein sequence database
P02317
Cellular localization
Nucleus . Chromosome . Loaded onto the nucleosomes of condensing spermatids. .
Tissue expression
Expressed by spermatids (at protein level).
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