Immunogen
Synthesized peptide derived from human LCN12 AA range: 56-106
Specificity
This antibody detects endogenous levels of LCN12 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009],
Function
function:May play a role in male fertility. May act as a retinoid carrier protein within the epididymis.,similarity:Belongs to the calycin superfamily. Lipocalin family.,
Human protein sequence Database
Q6JVE5
Mouse protein sequence database
Q6JVL5
Rat protein sequence database
B3EY83
Cellular localization
Secreted .