Immunogen
Synthesized peptide derived from human FOXD1 AA range: 82-132
Specificity
This antibody detects endogenous levels of FOXD1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Studies of the orthologous mouse protein indicate that it functions in kidney development by promoting nephron progenitor differentiation, and it also functions in the development of the retina and optic chiasm. It may also regulate inflammatory reactions and prevent autoimmunity. [provided by RefSeq, Apr 2014],
Function
function:Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly.,similarity:Contains 1 fork-head DNA-binding domain.,
Gene Name
FOXD1 FKHL8 FREAC4
Human protein sequence Database
Q16676
Mouse protein sequence database
Q61345
Rat protein sequence database
Q63251
Cellular localization
Nucleus.
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