Immunogen
Synthesized peptide derived from human ZEP2 AA range: 1975-2025
Specificity
This antibody detects endogenous levels of ZEP2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012],
Function
function:This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation.,induction:By mitogens and phorbol ester.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with TCF4.,tissue specificity:Expressed in brain and skeletal muscle.,
Human protein sequence Database
P31629
Mouse protein sequence database
Q3UHF7
Rat protein sequence database
Q00900
Cellular localization
Nucleus.
Tissue expression
Expressed in brain and skeletal muscle.
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