Immunogen
Synthesized peptide derived from human KR131 AA range: 99-149
Specificity
This antibody detects endogenous levels of KR131 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008],
Function
caution:The sequence of 1-41 of PubMed:12359730 has not been submitted.,function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the PMG family.,subunit:Interacts with hair keratins.,tissue specificity:Weak expression seen in the late matrix and entire cortex area of the hair follicle.,
Gene Name
KRTAP13-1 KAP13.1 KRTAP13.1
Human protein sequence Database
Q8IUC0
Mouse protein sequence database
Rat protein sequence database
Cellular localization
intermediate filament,
Tissue expression
Weak expression seen in the late matrix and entire cortex area of the hair follicle.
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