Immunogen
Synthesized peptide derived from human BDNF
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat BDNF
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Brain-derived neurotrophic factor (BDNF;Abrineurin)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>cAMP signaling pathway;>>PI3K-Akt signaling pathway;>>Neurotrophin signaling pathway;>>Huntington disease;>>Pathways of neurodegeneration - multiple diseases;>>Cocaine addiction;>>Alcoholism
Human protein sequence Database
P23560
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .; [BDNF precursor form]: Secreted . A proportion of BDNF is secreted as immature precursor (proBDNF). .
Tissue expression
Detected in blood plasma and in saliva (at protein level) (PubMed:11152678, PubMed:19467646). Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta.
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