Molecular weight (DA)
130kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AZI1. AA range:311-360
Specificity
AZI1 Polyclonal Antibody detects endogenous levels of AZI1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May play a role in spermatogenesis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May play a role in spermatogenesis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,
Protein name
5-azacytidine-induced protein 1
Other name
AZI1; CEP131; KIAA1118; 5-azacytidine-induced protein 1; Centrosomal protein of 131 kDa; Cep131; Pre-acrosome localization protein 1
Human protein sequence Database
Q9UPN4
Mouse protein sequence database
Q62036
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle, secretory vesicle, acrosome . Colocalized with pericentriolar material protein PCM1 at centriolar satellites. During spermiogenesis, becomes enriched with nephrocystin NPHP1 at the transition zone, a structure at the base of the ciliary axoneme important for regulating traffic into the ciliary compartment. Traffics towards and away from the centrosome/basal body and the transition zone of the ciliary axoneme in a microtubule-dependent manner. Localized at the Golgi-derived acrosome and the
Tissue expression
Brain,Epithelium,Lung,
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