Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PKNOX2. AA range:341-390
Specificity
PREP-2 Polyclonal Antibody detects endogenous levels of PREP-2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009],
Function
similarity:Belongs to the TALE/MEIS homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Homeobox protein PKNOX2
Other name
PKNOX2; PREP2; Homeobox protein PKNOX2; Homeobox protein PREP-2; PBX/knotted homeobox 2
Human protein sequence Database
Q96KN3
Mouse protein sequence database
Q8BG99
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Brain,Small intestine,
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