Molecular weight (DA)
74kD
Immunogen
The antiserum was produced against synthesized peptide derived from human FXR2. AA range:551-600
Specificity
FXR2 Polyclonal Antibody detects endogenous levels of FXR2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. [provided by RefSeq, Jul 2008],
Function
function:RNA-binding protein.,similarity:Belongs to the FMR1 family.,similarity:Contains 2 KH domains.,subunit:Interacts with FMR1 and FXR1. Interacts with CYFIP2 but not with CYFIP1. Interacts with TDRD3.,
Protein name
Fragile X mental retardation syndrome-related protein 2
Other name
FXR2; FMR1L2; Fragile X mental retardation syndrome-related protein 2
Human protein sequence Database
P51116
Mouse protein sequence database
Q9WVR4
Rat protein sequence database
Cellular localization
Cytoplasm.
Tissue expression
Brain,Epithelium,Lymph,PNS,Skin,
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