Molecular weight (DA)
35kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ATOH8 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical vessels.,
Function
function:Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical vessels.,
Gene Name
ATOH8 ATH6 BHLHA21
Protein name
Protein atonal homolog 8 (Class A basic helix-loop-helix protein 21) (bHLHa21) (Helix-loop-helix protein hATH-6) (hATH6)
Human protein sequence Database
Q96SQ7
Mouse protein sequence database
Q99NA2
Rat protein sequence database
Cellular localization
Nucleus . Nucleus speckle . Cytoplasm .
Tissue expression
Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical vessels.
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